5775-94-0

Basic information

• Product Name: 1,3,4-trimethylpyrano[2,3-c]pyrazol-6(1H)-one
• Synonyms: 1,3,4-trimethyl-1,6-dihydropyrano[2,3-c]pyrazol-6-one; pyrano[2,3-c]pyrazol-6(1H)-one, 1,3,4-trimethyl-
• CAS NO: 5775-94-0
• Molecular Formula: C₉H₁₀N₂O₂
• Molecular Weight: 178.1879
• Mol File: 5775-94-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 349.2°C at 760 mmHg
• Flash Point: 165°C
• Density: 1.3g/cm³
• Vapor Pressure: 4.79E-05mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: 1,3,4-trimethylpyrano[2,3-c]pyrazol-6(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-trimethylpyrano[2,3-c]pyrazol-6(1H)-one(5775-94-0)
• EPA Substance Registry System: 1,3,4-trimethylpyrano[2,3-c]pyrazol-6(1H)-one(5775-94-0)

Safety Data

• Hazardous Substances Data: 5775-94-0(Hazardous Substances Data)

Usage

Structure

Pyrazolone derivative with a pyran ring fused to a pyrazole ring

Applications

a. Synthesis of various organic compounds and pharmaceuticals

Potential medicinal properties

anti-inflammatory and antitumor activities
c. Corrosion inhibitor for metal surfaces

Fields of application

Chemistry, medicine, and material science

Reactivity

Versatile chemical with a range of potential applications

Upstream product

• 5203-98-5 3,4-dimethyl-1H-pyrano[2,3-c]pyrazol-6-one 
• 74-88-4 methyl iodide 
• 141-97-9 ethyl acetoacetate 
• 2749-59-9 1,3-dimethyl-5-pyrazolone 
• 60-34-4 methylhydrazine 

Relevant articles and documents

Condensation of N-3-substituted 5-pyrazolones with esters of β-keto acids. Synthesis of pyrano[2,3-c]pyrazol-6-ones

N-Substituted 5-pryazolones undergo thermal condensation with esters of β-keto acids, losing water and alcohol molecules, to form N-substituted pyrano[2,3-c]pyrazol-6-ones. The pyran ring in these products is readily cleaved by the action of alkali to give the corresponding salts of unsaturated acids. 2006 Springer Science+Business Media, Inc.

Pyranopyrazoles. II (1). Synthesis and Reactions of 1H,6H-Pyranopyrazol-6-ones

Various 1H,6H-pyranopyrazol-6-ones (III-XXIII) were obtained from β-keto esters and 1H-pyrazol-5-ones or hydrazines.Nitrations, chlorinations and brominations of these pyranopyrazoles were also carried out giving the corresponding derivatives (XXIV-LXIV).The pyrone ring is the more reactive one by the addition-elimination route.