57754-86-6 Usage
Uses
Nisoxetine Hydrochloride is a selective and potent inhibitor of norepinephrine transporter.
Biological Activity
A potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.
Biochem/physiol Actions
Nisoxetine?is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.
Check Digit Verification of cas no
The CAS Registry Mumber 57754-86-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,7,5 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57754-86:
(7*5)+(6*7)+(5*7)+(4*5)+(3*4)+(2*8)+(1*6)=166
166 % 10 = 6
So 57754-86-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
57754-86-6Relevant articles and documents
Treatment of obesity with aryloxyphenylpropylamines
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, (2008/06/13)
3-Aryloxy-3-phenylpropylamines and acid addition salts thereof are useful in blocking uptake of monoamines by brain neurons, and are thus effective in treating disorders of sleep, sexual performance, appetite, muscular function, and pituitary function.
