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7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine, commonly known as cloxazolam, is a psychoactive chemical compound that belongs to the benzodiazepine class of drugs. It possesses sedative, anxiolytic, and muscle relaxant properties, making it a valuable pharmaceutical agent for the treatment of various conditions.
Used in Pharmaceutical Industry:
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine is used as a therapeutic agent for the treatment of anxiety disorders, insomnia, and epilepsy. It functions by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that inhibits nervous system activity, thereby reducing anxiety and producing a calming effect.
Used as a Sedative:
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine is used as a sedative to induce a state of relaxation and drowsiness, which can be beneficial for individuals suffering from insomnia or experiencing heightened anxiety.
Used as an Anxiolytic:
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine is used as an anxiolytic to alleviate symptoms of anxiety and stress, providing a sense of calm and relaxation to individuals with anxiety disorders.
Used as a Muscle Relaxant:
7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine is used as a muscle relaxant to reduce muscle tension and spasms, which can be helpful in the management of conditions such as epilepsy or muscle-related disorders.
However, it is important to note that cloxazolam, like other benzodiazepines, can cause side effects such as drowsiness, dizziness, and impaired cognitive and motor function. Additionally, long-term use can lead to addiction and dependence. Therefore, it should be used with caution and under the supervision of a medical professional to ensure safe and effective treatment.

57756-37-3

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57756-37-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 57756-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,7,5 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57756-37:
(7*5)+(6*7)+(5*7)+(4*5)+(3*6)+(2*3)+(1*7)=163
163 % 10 = 3
So 57756-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H11ClN2/c10-8-1-2-9-7(5-8)6-11-3-4-12-9/h1-2,5,11-12H,3-4,6H2

57756-37-3Relevant academic research and scientific papers

Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT 2C receptor

Sabb, Annmarie L.,Vogel, Robert L.,Welmaker, Gregory S.,Sabalski, Joan E.,Coupet, Joseph,Dunlop, John,Rosenzweig-Lipson, Sharon,Harrison, Boyd

, p. 2603 - 2607 (2007/10/03)

Evaluation of selected compounds from our Corporate Compound Library in a human 5-HT2C receptor binding assay led to the discovery of WAY-629, a cyclohexyl[b][1,4]benzodiazepinoindole (Ki 56nM, Emax 90%), which is selectiv

[1,4]Diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents

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Page/Page column 15, (2008/06/13)

Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: where R1 through R7 are defined herein. The compounds of Formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of di

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