57768-96-4

Basic information

• Product Name: sodium 2-hydroxy-3-methylbutyrate
• Synonyms: sodium 2-hydroxy-3-methylbutyrate;2-Hydroxy-3-methylbutanoic acid sodium salt
• CAS NO: 57768-96-4
• Molecular Formula: C₅H₉O₃*Na
• Molecular Weight: 140.11293
• EINECS: 260-937-8
• Mol File: 57768-96-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 237.6°Cat760mmHg
• Flash Point: 111.8°C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: sodium 2-hydroxy-3-methylbutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium 2-hydroxy-3-methylbutyrate(57768-96-4)
• EPA Substance Registry System: sodium 2-hydroxy-3-methylbutyrate(57768-96-4)

Safety Data

• Hazardous Substances Data: 57768-96-4(Hazardous Substances Data)

Upstream product

• 3715-29-5 sodium 3-methyl-2-oxobutyrate 

Relevant articles and documents

A new family of D-2-hydroxyacid dehydrogenases that comprises D-mandelate dehydrogenases and 2-ketopantoate reductases

The gene for the D-mandelate dehydrogenase (DManDH) of Enterococcus faecalis IAM10071 was isolated by means of an activity staining procedure and PCR and expressed in Escherichia coli cells. The recombinant enzyme exhibited high catalytic activity toward various 2-ketoacid substrates with bulky hydrophobic side chains, particularly C3-branched substrates such as benzoylformate and 2-ketoisovalerate, and strict coenzyme specificity for NADH and NAD+. It showed marked sequence similarity with known NADP-dependent 2-ketopantoate reductases (KPR). These results indicate that together with KPR, D-ManDH constitutes a new family of D-2-hydroxyacid dehydrogenases that act on C3-branched 2-ketoacid substrates with various specificities for coenzymes and substrates.