57774-35-3

Usage

Uses

Used in Display Technologies:
4'-Bromo-4-cyano-biphenyl is used as a key component in the synthesis of liquid crystals for display technologies, particularly in LCD screens. Its properties contribute to the development of high-quality displays with improved performance and reliability.
Used in Pharmaceutical and Agrochemical Industries:
4'-Bromo-4-cyano-biphenyl serves as an intermediate in the production of pharmaceuticals and agrochemicals, where its unique structure aids in the development of new drugs and pesticides with enhanced efficacy and selectivity.
Used in Organic Synthesis as a Catalyst:
4'-Bromo-4-cyano-biphenyl has been investigated for its potential use as a catalyst in organic reactions due to its electronic and steric properties, which can influence the reaction pathways and improve the yield of desired products.
However, it is important to handle 4'-bromo-4-cyano-biphenyl with care, as it is considered toxic if ingested or inhaled, and it may cause skin and eye irritation upon contact. Proper safety measures should be taken during its use and disposal to minimize potential health risks.

Upstream product

• 2863-98-1 4-hydrazinobenzonitrile hydrochloride 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 589-87-7 1,4-bromoiodobenzene 
• 126747-14-6 4-cyanophenylboronic acid 

Downstream Products

• 406482-73-3 (4'-cyano-[1,1'-biphenyl]-4-yl)boronic acid 
• 130447-14-2 4'''-Dimethylamino-[1,4';1',1'';4'',1''']quaterphenyl-4-carbonitrile 
• 1214278-85-9 1-(tert-butoxycarbonyl)-2-(4'-cyanobiphenyl-4-yl)-1hindole-6-carbonitrile 
• 1214278-84-8 1-(tert-butoxycarbonyl)-2-(4'-cyanobiphenyl-4-yl)-1hindole-5-carbonitrile 
• 2920-38-9 4-cyano-1,1'-biphenyl 
• 1219958-87-8 C₃₂H₂₁NO 
• 1448709-43-0 4'-(3,6-bis(4-(2-ethylhexyloxy)phenyl)-9H-carbazole-9-yl)biphenyl-4-carboxylic acid 

Relevant academic research and scientific papers

Understanding the remarkable difference in liquid crystal behaviour between secondary and tertiary amides: The synthesis and characterisation of new benzanilide-based liquid crystal dimers

A number of liquid crystal dimers have been synthesised and characterised containing secondary or tertiary (N-methyl) benzanilide-based mesogenic groups. The secondary amides all form nematic phases, and we present the first example of an amide to show the twist-bend nematic (NTB) phase. Only two of the correspondingN-methylated dimers formed a nematic phase and with greatly reduced nematic-isotropic transition temperatures. Characterisation using 2D ROESY NMR experiments, DFT geometry optimisation and X-ray diffraction reveal that there is a change in the preferred conformation of the benzanilide core on methylation, fromZtoE. The rotational barrier around the N-C(O) bond has been measured using variable temperature1H NMR spectroscopy. This dramatic change in shape accounts for the remarkable difference in liquid crystalline behaviour between these secondary and tertiary amide-based materials.

Palladium and copper-catalyzed ligand-free coupling of phenylhydrazines in water

An efficient protocol has been developed for the synthesis of biaryls via Pd/Cu catalyzed coupling of phenylhydrazines in water. Homo and cross couplings were successfully achieved in a ligand-free catalytic system, at room temperature with water as sole reaction medium. This journal is

Making nonsymmetrical bricks: Synthesis of insoluble dipolar sexiphenyls

A versatile synthesis of nonsymmetrical, terminally substituted p-sexiphenyl (6P) derivatives has been developed. The synthesis makes use of a nonsymmetrical starting material as well as modular functionalization using Suzuki cross-coupling to yield a soluble precursor, which finally is converted to the insoluble target 6P derivatives. These derivatives display similar electronic and optical properties to the parent 6P, yet the permanent dipole along their molecular axis allows for tuning of their self-assembly on various substrate surfaces.

NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND

A non-resonant two-photon absorption recording material containing at least (a) a non-resonant two-photon absorption compound, and (b) a recording component in which at least either a refractive index or fluorescence intensity changes, wherein the non-resonant two-photon absorption compound (a) is a compound having a structure represented by formula (1) as described.

Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use

The present invention is directed to compound of the formula I: STR1 wherein R1, R2, R3, R4, R5, X, Y, and STR2 are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.