57775-27-6Relevant academic research and scientific papers
Process for preparing the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate
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, (2008/06/13)
The process is characterized in that the diethylamine salt or the ammonium salt of 2,5-dihydroxybenzenesulphonic acid is used as starting material, which salt is tosylated in an ammoniacal medium to lead in both cases to the production of the ammonium salt of 2,5-dihydroxybenzenesulphonic acid monotosylate, which in its turn is converted initially to the corresponding piperazine disalt which is separated in an aqueous medium, and finally in an aqueous-alcoholic medium the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate, also known as piperazine sultosylate, is obtained. Medicinal applications.
Process for preparing the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate
-
, (2008/06/13)
The process is characterized in that the diethyl-amine salt or the ammonium salt of 2,5-dihydroxybenzene-sulphonic acid is used as starting material, which salt is tosylated in an ammoniacal medium to lead in both cases to the production of the ammonium salt of 2,5--dihydroxybenzenesulphonic acid monotosylate, which in its turn is converted initially to the corresponding piperazine disalt which is separated in an aqueous medium, and finally in an aqueous-alcoholic medium the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate, also known as piperazine sultosylate, is obtained. Medicinal applications.
