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Topiroxostat Impurity 9, also known as N-Oxalylglycine, is a chemical compound that serves as an impurity in the pharmaceutical industry. It originates from the drug Topiroxostat, which is utilized for treating hyperuricemia and gout. N-Oxalylglycine acts as a potent inhibitor of proline dehydrogenase and has been explored for its potential therapeutic applications in cancer treatment. Furthermore, it functions as a research tool to study the role of proline metabolism in various disease conditions. As a pharmaceutical impurity, N-Oxalylglycine plays a crucial role in drug development and quality control, adhering to stringent regulatory guidelines to ensure safety and efficacy in medical applications.

577778-82-6

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577778-82-6 Usage

Uses

Used in Pharmaceutical Industry:
Topiroxostat Impurity 9 is used as a pharmaceutical impurity for the development and quality control of drugs. It is essential in ensuring the safety and effectiveness of medical applications, adhering to strict regulatory guidelines.
Used in Cancer Treatment Research:
N-Oxalylglycine is utilized as a research compound for studying its potential therapeutic applications in cancer treatment. Its role as a potent inhibitor of proline dehydrogenase makes it a valuable tool in investigating new approaches to combat cancer.
Used in Disease Condition Research:
Topiroxostat Impurity 9 serves as a research tool to explore the role of proline metabolism in various disease conditions. This helps in understanding the underlying mechanisms and potentially identifying new therapeutic targets for treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 577778-82-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,7,7,7 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 577778-82:
(8*5)+(7*7)+(6*7)+(5*7)+(4*7)+(3*8)+(2*8)+(1*2)=236
236 % 10 = 6
So 577778-82-6 is a valid CAS Registry Number.

577778-82-6Upstream product

577778-82-6Downstream Products

577778-82-6Relevant academic research and scientific papers

NOVEL 1,2,4-TRIAZOLE COMPOUND

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Page 12, (2010/02/08)

A novel 1,2,4-triazole compound which is useful as a therapeutic agent for hyperuricemia and gout due to hyperuricemia is provided. A compound is represented by the following general formula (1): wherein R2 represents an unsubstituted or substituted pyridyl group, R1 represents a similar pyridyl group, a pyridine-N-oxide group corresponding to these pyridyl groups, or a phenyl group, and R3 represents hydrogen or a lower alkyl group substituted with pivaloyloxy group and R3 bonds to a nitrogen atom in the ring. A process for production of a compound by reacting a nitrile and a hydrazide, and a therapeutic agent, particularly a xanthine oxidase inhibitor are also provided.

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