57784-96-0

Usage

InChI:InChI=1/C9H9NO4/c10-8(9(13)14)5-1-2-6(4-11)7(12)3-5/h1-4,8,12H,10H2,(H,13,14)

Upstream product

• 108647-55-8 (2S)-(+)-2-(3-Methoxyphenyl)glycin 
• 71301-82-1 (S)-3-hydroxyphenylglycine 
• 108647-56-9 (S)-tert-Butoxycarbonylamino-(4-formyl-3-hydroxy-phenyl)-acetic acid 
• 108594-41-8 (2S)-(+)-2-<(1S,2S)-(2-Hydroxy-1-hydroxymethyl-2-phenylethyl)amino>-2-(3-methoxyphenyl)essigsaeure 
• 46988-94-7 (2S)-(+)-N-tert-Butoxycarbonyl-2-(3-hdroxyphenyl)glycin 
• 73036-70-1 (2S)-(+)-N-tert-Butoxycarbonyl-2-(3-hydroxy-4-hydroxymethylphenyl)glycin 

Relevant academic research and scientific papers

Nonproteinogenic Amino Acids, IV. - EPC Synthesis of L-(+)-Forphenicine

Enantiomerically pure L-(+)-forphenicine (12) is synthesized starting from purchasable 3-methoxybenzaldehyde (1) by the use of (4S,5S)-(+)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane (2) as a chiral auxiliary and prussic acid. 12 is identical with the natural product which has been isolated from the culture broth of an Actinomyces species and which is known to be a potent inhibitor of alkaline phosphatase.