577968-06-0Relevant articles and documents
Diastereoselective titanium-mediated construction of cis-2,3-ring annelated 1-(2′-chloroethyl)cyclopropanols
Lecornue, Frederic,Ollivier, Jean
, p. 584 - 585 (2003)
Titanium (IV)-mediated cyclopropanation induced by reaction of cycloalkylmagnesium bromides 1a-e in the presence of titanium tetraisopropoxide with ethyl β-chloropropionate 2 yielded cis-fused 1-(2′-chloroethyl)cyclopropanols 3b-e with diastereoselectivity highly depending on the ring size. Unexpected rearrangement products 5d,e were isolated in some cases.