577979-00-1Relevant academic research and scientific papers
α-Rhamnosidase inhibitory activities of polyhydroxylated pyrrolidine
Kim, Jin Hyo,Curtis-Long, Marcus J.,Woo, Duck Seo,Jin, Hwan Lee,Byong, Won Lee,Yong, Jin Yoon,Kyu, Young Kang,Park, Ki Hun
, p. 4282 - 4285 (2007/10/03)
We designed and synthesized polyhydroxylated pyrrolidines 1-12 from l-tyrosine, l-phenylalanine, and d-tyrosine through iodine-mediated intramolecular cyclization followed by Woodward-Prevost reaction. The synthetic polyhydroxylated pyrrolidines were iden
Chirospecific synthesis of the (2S,3R)- and (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acids from sugar: Application to (-)-bestatin
Lee, Jin Hwan,Lee, Byong Won,Jang, Ki Chang,Jeong, Ill-Yun,Yang, Min Suk,Lee, Sang Gyeong,Park, Ki Hun
, p. 829 - 836 (2007/10/03)
The enantiomerically pure (2S,3R)- and (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acids (AHPBA) were first obtained from sugar in a chirospecific manner. Additionally, the obtained (2S,3R)-AHPBA 1 was easily applied to the synthesis of (-)-bestatin.
