57818-37-8Relevant articles and documents
Optimised total syntheses of the F-furan fatty acids F5 and F6 and some deuterated derivatives Dedicated, with the greatest respect, to the memory of Professor Alan R. Katritzky
Knight, David W.,Smith, Andrew W.T.
, p. 7436 - 7444 (2015/08/24)
Optimised syntheses of F5- and F6-furan fatty acids 2 and 3 are described in full. Key steps include furan formation from a single 3-alkyne-1,2-diol 6 using 5-endo-dig cyclisations triggered by silver(I) nitrate or iodine. Introducti
Total synthesis of the naturally occurring furanoid fatty acid, F5
Marson, Charles M.,Harper, Steven
, p. 333 - 334 (2007/10/03)
The furanoid fatty acid F5 has been synthesized using a mercury(II) catalyzed isomerization of 2-(1,2-oxiranylcyclododecyl)-3-nonyn-2-ol.
Sequential Pd(0)-catalyzed reactions for the construction of multiple substituted furans. A short synthesis of the F5 furan fatty acid
Bach, Thorsten,Krueger, Lars
, p. 1729 - 1732 (2007/10/03)
4,5-Dibromofurfural (1) undergoes a regioselective Pd(0)-catalyzed C-C bond forming reaction at its C-5 position to yield corresponding furans 3. The second bromine substituent in C-4 position can be substituted by a methyl group in a subsequent Pd(0)-catalyzed cross coupling reaction. The furan fatty acid 12 and its benzyl ester 13 were prepared in a short synthetic sequence using this method.