57818-41-4

Basic information

• Product Name: 3,4-DiMethyl-5-propyl-2-furanundecanoic Acid
• Synonyms: 3,4-DiMethyl-5-propyl-2-furanundecanoic Acid
• CAS NO: 57818-41-4
• Molecular Formula: C₂₀H₃₄O₃
• Molecular Weight: 610.16488
• Product Categories: Glycerols, Fatty Acid Derivatives & Lipids
• Mol File: 57818-41-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-DiMethyl-5-propyl-2-furanundecanoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DiMethyl-5-propyl-2-furanundecanoic Acid(57818-41-4)
• EPA Substance Registry System: 3,4-DiMethyl-5-propyl-2-furanundecanoic Acid(57818-41-4)

Safety Data

• Hazardous Substances Data: 57818-41-4(Hazardous Substances Data)

Usage

Uses

3,4-Dimethyl-5-propyl-2-furanundecanoic acid is also known as F4 furan fatty acid. Furan fatty acids are generated in large amounts in algae and fish, but they are also produced by plants and microorganisms. Furan fatty acids are known to exhibit radical-scavenging ability and anti-inflammatory properties.

Upstream product

• 2495-35-4 benzylacrylate 
• 50-00-0 formaldehyd 
• 68532-48-9 11-(5-propylfuran-2-yl)undecanoic acid 

Relevant articles and documents

A General Convergent Strategy for the Synthesis of Tetra-Substituted Furan Fatty Acids (FuFAs)

Using a palladium catalyzed - acid mediated isomerization sequence, tetrasubstituted furans suitable for furan fatty acid (FuFA) total synthesis can be effectively constructed in high yield. This convergent approach installs the essential carbon side chains at the α1- and α2 -positions, the β1-methyl group, and importantly, an electron withdrawing group at the β2-position tempering the reactivity of the electron rich furan in the FuFAs. When this EWG is an ester, it was conveniently transformed into the required β1-methyl group in three high yielding synthetic steps. Using this approach, the total synthesis of 11D5 and 11D3 was accomplished in 7-steps from commercially available starting materials in overall yields of 52 % and 48 %, respectively. Furthermore, this methodology also provided an efficient synthetic route to the decarboxy analogues of both 11D5 and 11D3.