57821-20-2 Usage
Molecular Weight
220.19 g/mol
Structure
Tricyclic compound with a pyrido[2,3-d]pyrimidine ring system and three carbonyl groups at positions 2, 4, and 7
Functional Groups
Carbonyl (C=O) groups, aromatic ring system
Appearance
Yellow to brown crystalline solid
Solubility
Soluble in organic solvents like DMSO, ethanol, and methanol
Stability
Stable under normal conditions, sensitive to strong acids and bases
Reactivity
Can undergo various chemical reactions such as nucleophilic addition, electrophilic substitution, and condensation reactions
Organic synthesis
Versatile building block for the development of new pharmaceuticals and agrochemicals
Medicinal chemistry
Intermediate for the synthesis of various heterocyclic compounds with potential biological activities
Antiviral and antitumor properties
Promising candidate for drug discovery and development
Hazards
May cause eye, skin, and respiratory irritation; harmful if swallowed or inhaled
Storage
Store in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames
Safety Measures
Use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats when handling this compound
Regulatory Status
Not specifically regulated, but safety and handling guidelines should be followed according to its chemical properties and potential hazards
Check Digit Verification of cas no
The CAS Registry Mumber 57821-20-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,8,2 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57821-20:
(7*5)+(6*7)+(5*8)+(4*2)+(3*1)+(2*2)+(1*0)=132
132 % 10 = 2
So 57821-20-2 is a valid CAS Registry Number.
57821-20-2Relevant articles and documents
Reactivities of 6-amino-1,3-dimethyl-5-thioformyluracil toward nucleophiles and its application to synthesis of pyrido[2,3-d]pyrimidines
Hirota, Kosaku,Kubo, Keiko,Sajiki, Hironao
, p. 542 - 544 (2007/10/03)
The reaction of the 5-thioformyluracil 1 with phenylhydrazine and various amines readily afforded the hydrazone 3a and Schiff bases 3b-d, respectively. Further, carbanions and Wittig reagents reacted with 1 to give pyrido[2,3-d]pyrimidines 4 and 9. The co
Pyrimidines. 17. Novel pyrimidine to pyridine transformation reaction. One-step synthesis of pyrido[2,3-d]pyrimidines
Hirota,Kitade,Senda,et al.
, p. 846 - 851 (2007/10/02)
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Pyridopyrimidines. 5. N-oxidations and rearrangements in the pyrido[2,3-d]pyrimidine series.
Broom,Bartholomew
, p. 3027 - 3030 (2007/10/08)
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