57826-98-9

Basic information

• Product Name: 3-(pyrimidin-4-yl)-1H-indole
• Synonyms: 3-(pyrimidin-4-yl)-1H-indole
• CAS NO: 57826-98-9
• Molecular Weight: 195.224
• Mol File: 57826-98-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(pyrimidin-4-yl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(pyrimidin-4-yl)-1H-indole(57826-98-9)
• EPA Substance Registry System: 3-(pyrimidin-4-yl)-1H-indole(57826-98-9)

Safety Data

• Hazardous Substances Data: 57826-98-9(Hazardous Substances Data)

Relevant articles and documents

Consecutive SNH and Suzuki-Miyaura cross-coupling reactions-an efficient synthetic strategy to pyrimidines bearing pyrrole and indole fragments

The combination of the Suzuki-Miyaura cross-coupling and nucleophilic aromatic substitution of hydrogen reactions is a versatile tool for the syntheses of 4-(1R-pyrrol-2-yl)-and 4-(1R-indol-3-yl)-5-(hetero)aryl-substituted pyrimidines from commercially available 5-bromopyrimidine. The S NH [AE, (addition-elimination)] and SN H [AO, (addition-oxidation)] reactions of 5-bromopyrimidine with pyrroles and indoles were studied by gas chromatography-mass spectrometry. The structures of the intermediate σH adducts as well as the pyrrole-(hetero)arylpyrimidine and indole-(hetero)arylpyrimidine dyads were established for the first time by X-ray crystal structure analysis.