57833-86-0Relevant academic research and scientific papers
Method for synthesizing 2-(2',6'-dimethylphenyl amino)methyl propionate
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, (2017/01/12)
The invention discloses a method for synthesizing 2-(2',6'-dimethylphenyl amino)methyl propionate, and belongs to the organic synthesis technical field. L-lactic acid as a starting material is esterified with methanol to obtain L-methyl lactate; then the L-methyl lactate is subjected to a reaction with chlorosulfonic acid under catalysis of concentrated sulfuric acid to generate 2-(3-sulfonylphenyl amino)methyl propionate; next, the 2-(3-sulfonylphenyl amino)methyl propionate is subjected to a reaction with chlorine gas to only generate 2-(2',6'-dichloro-3-sulfonylphenyl amino)methyl propionate, and the reaction yield is improved; then sulfonyl is removed under the action of dilute sulfuric acid; and finally, the obtained product is subjected to a reaction with a Grignard reagent to obtain 2-(2',6'-dimethylphenyl amino)methyl propionate. The method has the advantages of mild and simple operating condition, and the yield is increased and is increased to 91% or more.
Haloacetanilides as microbicidal active substances
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, (2008/06/13)
Compounds of the formula STR1 wherein Z1 represents methyl or chlorine, Z2 represents chlorine or bromine, Z3 represents hydrogen or C1 -C3 alkyl, and X represents fluorine, chlorine, bromine or iodine, exhibit microbicidal activity, preferably against phytopathogenic fungi.
