57859-83-3

Usage

Also known as

1-(1-phenyl-2-propenyl)-2-tetralone

Structure

A derivative of tetralone

Bicyclic aromatic ketone

Features two fused rings with a carbonyl group (C=O) attached to one of the rings

Phenacyl group

A phenyl group (a benzene ring with a single carbon-carbon double bond) bonded to an ethyl group (CH2CH3)

Phenacyl group attachment

Bonded to the second carbon of the tetralone ring

Usage

Organic synthesis reagent

Preparation of pharmaceutical and industrial products

1-Phenacyl-2-tetralone serves as a starting material or intermediate in the synthesis of various compounds

Precursor to bioactive compounds

It can be converted into compounds with biological activity, which may have potential therapeutic applications

Applications

Medicinal chemistry

Potential applications

Due to its ability to form bioactive compounds, 1-Phenacyl-2-tetralone may be useful in the development of new drugs or drug candidates

Chemical properties and reactivity

Useful building block for complex organic molecules
The compound's properties and reactivity allow it to participate in various chemical reactions, making it a valuable component in the synthesis of complex organic molecules

Upstream product

• 21403-95-2 1-(3,4-dihydronaphthalene-2-yl)pyrrolidine 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 54670-29-0 5-(1-acetyl-2-phenyl-4,5-dihydro-benzo[e]indol-3-yl)-2-hydroxy-benzoic acid 
• 54669-68-0 2-hydroxy-5-(2-phenyl-benzo[e]indol-3-yl)-benzoic acid 
• 54670-54-1 3-(3-Carbamoyl-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz[e]indole 
• 54670-08-5 4,5-dihydro-3-(4-hydroxy-3-methoxycarbonylphenyl)-2-phenylbenz[e]indole 
• 54670-28-9 4,5-Dihydro-3-(3-ethoxycarbonyl-4-hydroxyphenyl)-2-phenylbenz[e]indole 
• 54670-55-2 4,5-Dihydro-3-(3-N-ethylcarbamoyl-4-hydroxyphenyl)-2-phenylbenz[e]indole 
• 54670-57-4 4,5-Dihydro-3-(3-N-hydroxycarbamoyl-4-hydroxyphenyl)-2-phenylbenz[e]indole 
• 54669-70-4 3-(4-acetoxy-3-carboxyphenyl)-4,5-dihydro-2-phenylbenz[e]indole 
• 54670-56-3 3-(3-N,N-Diethylcarbamoyl-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz[e]indole 
• 54670-05-2 4,5-Dihydro-3-(4-N,N-dimethylcarbamoylthio-3-methoxycarbonylphenyl)-2-phenylbenz[e]indole 
• 54670-03-0 4,5-dihydro-3-(4-N,N-dimethylthiocarbamoyloxy-3-methoxycarbonylphenyl)-2-phenylbenz[e]indole 
• 53597-27-6 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz[e]indole 

Relevant academic research and scientific papers

COMPOUNDS FOR ALZHEIMER'S DISEASE

The invention provides novel compounds useful for the treatment of neurodegenerative disorders including Alzheimer's disease and dementia. The compounds have a substituents chosen from -L-C(═O)OH, -L-CH═CHC(═O)OH, -L-C(═O)NH2, -L-C(═O)NH(C1-3 alkyl), -L-C(═O)N(C1-3 alkyl)2, -L-S(═O)2(C1-3alkyl), -L-S(═O)2NH2, -L-S(═O)2N(C1-3 alkyl)2, -L-S(═O)2NH(C1-3 alkyl), -L-C(═O)NHOH, -L-C(═O)CH2NH2, -L-C(═O)CH2OH, -L-C(═O)CH2SH, -L-C(═O)NHCN, -L-NHC(═O)ORo, -L-C(═O)NHRo, -L-NH(C═O)NHRo, -L-C(═O)N(Ro)2, -L-NH(C═O)N(Ro)2, -L-sulfo, -L-(2,6 difluorophenol), -L-phosphono, and -L-tetrazolyl, where L is a linker.

COMPOUNDS FOR DISEASES AND DISORDERS

The invention provides novel compounds useful for the treatment of disorders associated with a defect in vesicular transport (e.g., axonal transport). The compounds have a substituents chosen from -L-C(=O)OH, -L-CH=CHC(=O)OH, -L-C(=O)NH2, -L-C(=O)NH(C1-3 alkyl), -L-C(=O)N(C1-3 alkyl)2, -L-S(=O)2(C1-3alkyl), -L-S(=O)2NH2, -L-S(=O)2N(C1-3 alkyl)2, -L-S(=O)2NH(C1-3 alkyl), -L-C(=O)NHOH, -L-C(=O)CH2NH2, -L-C(=O)CH2OH, -L-C(=O)CH2SH, -L-C(=O)NHCN, -L-NHC(=O)ORo, -L-C(=O)NHRo, -L-NH(C=O)NHRo, -L-C(=O)N(Ro)2, -L-NH(C=O)N(Ro)2, -L-sulfo, -L-(2,6 difluorophenol), -L-phosphono, and -L-tetrazolyl, where L is a linker.

COMPOUNDS FOR ALZHEIMER'S DISEASE

The invention provides novel compounds useful for the treatment of neurodegenerative disorders including Alzheimer's disease and dementia. The compounds have a substituents chosen from -L-C(=O)OH, -L-CH=CHC(=O)OH, -L-C(=O)NH2, -L-C(=O)NH(C1-3 alkyl), -L-C(=O)N(C1-3 alkyl)2, -L-S(=O)2(C1-3alkyl), -L-S(=O)2NH2, -L-S(=O)2N(C1-3 alkyl)2, -L-S(=O)2NH(C1-3 alkyl), -L-C(=O)NHOH, -L-C(=O)CH2NH2, -L-C(=O)CH2OH, -L-C(=O)CH2SH, -L-C(=O)NHCN, -L-NHC(=O)ORo, -L-C(=O)NHRo, -L-NH(C=O)NHRo, -L-C(=O)N(Ro)2, -L-NH(C=O)N(Ro)2, -L-sulfo, -L-(2,6 difluorophenol), -L-phosphono, and -L-tetrazolyl, where L is a linker.

Substituted N-aminoalkylpyrroles

Substituted N-aminoalkylpyrroles of the formula: STR1 IN WHICH X, Z, R1, -R5 and n are as defined below, and their physiologically tolerable acid addition salts are disclosed to have antiarrhythmic, central nervous system depressant,

Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent

Novel N-phenylpyrroles are disclosed that are effective in the treatment of inflammation and pain in mammals and have the formula SPC1 Wherein R is hydrogen, alkyl of one to six carbon atoms, thienyl, phenyl or phenyl substituted by halogen, trifluorometh