57872-78-3

Usage

Uses

Used in Pharmaceutical Industry:
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-hexyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name) is used as a potential pharmaceutical agent for its unique molecular structure and functional groups. The presence of the purine ring with an amino group may allow for interactions with specific biological targets, while the hydroxyl and alkyl groups could contribute to its solubility and bioavailability in the body.
Used in Biological Research:
In the field of biological research, (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-hexyl-3,4-dihydroxytetrahydrofuran-2-carboxamide (non-preferred name) can be employed as a tool compound to study the effects of its unique structural features on various biological processes. Its potential interactions with proteins, nucleic acids, or other biomolecules can provide insights into the development of new therapeutic agents or understanding of disease mechanisms.

Upstream product

• 19234-66-3 2',3'-isopropylideneadenosine-5'-carboxylic acid 
• 159647-45-7 (3aS,4S,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid 4-nitro-phenyl ester 
• 111-26-2 hexan-1-amine 
• 39491-49-1 2',3'-O-isopropylideneadenosine-5'-carbonyl chloride 

Relevant academic research and scientific papers

Nucleosides and nucleotides. 200. Reinvestigation of 5′-N-ethylcarboxamidoadenosine derivatives: Structure-activity relationships for P3 purinoceptor-like proteins

The non-P1 and non-P2 muscle relaxant effect of ATP in rabbit thoracic aorta has recently been attributed to a putative P3 purinoceptor, which is activated by either adenosine or ATP. Since the physiological roles of this

Modification of the 5' Position of Purine Nucleosides. 2. Synthesis and Some Cardiovascular Properties of Adenosine-5'-(N-substituted)carboxamides

We have shown previously that the esters of adenosine-5'-carboxylic acid (10) represent a new class of potent nontoxic coronary vasodilators.For example, the ethyl ester (12), which is active by an intraduodenal or intravenous route in dogs, causes a larg

Adenosine-5'-carboxylic acid amides

Adenosine-5'-carboxylic acid amides represented by the formula STR1 wherein R1 and R2 are each selected from the group consisting of hydrogen, loweralkyl, lowerhaloalkyl, lowerhydroxyalkyl, lowercycloalkyl, loweralkylcycloalkyl, loweralkenyl, lowerhaloalkenyl, lowerhydroxyalkenyl, loweralkynyl, lowerhaloalkynyl, benzylamino, phenyl, loweralkylphenyl, loweralkoxyloweralkyl, substituted phenyl, 2-methylfuran or di(C1 -C4)alkylamino(C1 -C4)alkyl, adamantyl or R1 and R2 taken together form a 5 or 6 membered heterocyclic moiety; R3 and R4 are hydrogen or acyl, or taken together form an isopropylidene or a benzylidene group; or a pharmaceutically acceptable acid addition salt thereof.