578732-13-5

Upstream product

• 10257-28-0 D-Galactose 
• 108223-94-5 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose 
• 89825-84-3 1-O-acetyl-2,3,5,6-tetra-O-benzoyl-β-D-galactofuranose 
• 10368-86-2 1,2:5,6-di-O-isopropylidene-α-D-galactofuranose 
• 226211-26-3 O-(2,3,5,6-tetra-O-benzoyl-β-D-galactofuranosyl)-trichloroacetimidate 

Downstream Products

• 578732-14-6 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranosyl-(1->3)-5,6-di-O-acetyl-1,2-O-isopropylidene-α-D-galactopyranose 

Relevant academic research and scientific papers

First synthesis of β-D-Galf-(1→3)-D-Galp - The repeating unit of the backbone structure of the O-antigenic polysaccharide present in the lipopolysaccharide (LPS) of the genus Klebsiella

β-D-Galactofuranosyl-(1→3)-D-galactopyranose (1), the repeating unit of the backbone structure of the O-antigenic polysaccharide present in the lipopolysaccharide (LPS) of the genus Klebsiella, has been efficiently synthesized using 1,2:5,6-di-O-isopropylidine-α-D-galactofuranose (3) as the glycosyl acceptor and 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranosyl trichloroacetimidate (6) as the glycosyl donor with TMSOTf as catalyst by the well-known Schmidt glycosylation method. The preparation of 3 was improved by increasing the ratio of DMF to acetone and employing a solid-supported catalyst.