57877-20-0

Basic information

• Product Name: 2-biphenyl-2-yl-3-hydroxy-2,3-dihydro-isoindol-1-one
• Synonyms: 2-biphenyl-2-yl-3-hydroxy-2,3-dihydro-isoindol-1-one
• CAS NO: 57877-20-0
• Molecular Weight: 301.345
• Mol File: 57877-20-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-biphenyl-2-yl-3-hydroxy-2,3-dihydro-isoindol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-biphenyl-2-yl-3-hydroxy-2,3-dihydro-isoindol-1-one(57877-20-0)
• EPA Substance Registry System: 2-biphenyl-2-yl-3-hydroxy-2,3-dihydro-isoindol-1-one(57877-20-0)

Safety Data

• Hazardous Substances Data: 57877-20-0(Hazardous Substances Data)

Upstream product

• 90-41-5 2-phenylaniline 
• 91-13-4 α,α'-dibromo-o-xylene 
• 14835-59-7 2-(biphenyl-2-yl)-1H-isoindole-1,3(2H)-dione 

Downstream Products

• 63558-92-9 isoindolo<2,1-f>phenanthridin-10(14bH)-one 

Relevant articles and documents

Oxidative Desymmetrization of Isoindolines Realized by tert -Butyl Nitrite (TBN) Initiated Radical sp 3C-H Activation Relay (CHAR)

An oxidative desymmetrization of isoindolines was realized by TBN initiated radical sp 3C-H activation relay (CHAR), providing a series of ω-hydroxylactams in high yields. This reaction exhibits broad substrate scope and functional group tolerance, and even N -alkyl iso-indolines can be well tolerated. The mechanistic study shows that the C-H bond oxidation, dioxygen trapping and intramolecular 1,5-H shift might be the key steps to achieve the oxidative desymmetrization.