57877-29-9Relevant academic research and scientific papers
Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates
Igumnova, Elizaveta M.,Mishchenko, Ekaterina,Haug, Tor,Blencke, Hans-Matti,Sollid, Johanna U. Ericson,Fredheim, Elizabeth G. Aarag,Lauksund, Silje,Stensv?g, Klara,Str?m, Morten B.
, p. 4930 - 4941 (2018)
There is an urgent need for novel antimicrobial agents to address the threat of bacterial resistance to modern society. We have used a structural motif found in antimicrobial marine hit compounds as a basis for synthesizing a library of antimicrobial sulf
Catalytic enantioselective alkene aminohalogenation/cyclization involving atom transfer
Bovino, Michael T.,Chemler, Sherry R.
supporting information; experimental part, p. 3923 - 3927 (2012/05/20)
Problem solved: The title reaction was used for the synthesis of chiral 2-bromo, chloro, and iodomethyl indolines and 2-iodomethyl pyrrolidines (see scheme). Stereocenter formation is believed to occur by enantioselective cis aminocupration and C-X bond formation is believed to occur by atom transfer. The ultility of the products as versatile synthetic intermediates was demonstrated, as was a radical cascade cyclization sequence. Copyright
AMINOTETRAHYDROINDAZOLOACETIC ACIDS
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Page/Page column 31, (2010/02/17)
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, R1-R3 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manuf
MONOARYL AMINOTETRALINES
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Page/Page column 22-23, (2010/03/04)
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.
Selective Sulfonylating Agents
Guthrie, R. D. (Gus),Thang, San
, p. 2133 - 2136 (2007/10/02)
A variety of bulky sulfonyl chlorides have been investigated as sulfonylating reagents for polyol systems in an endeavour to find a selective reagent that would also give rise to a reactive sulfonate ester group.
