57877-29-9

Upstream product

• 1460-02-2 1,3,5-Tri-tert-butylbenzene 
• 1014-60-4 1,3-di-tert-butylbenzene 

Downstream Products

• 1075191-24-0 methyl (S)-3-(1-methyl-1H-imidazol-5-yl)-2-(3,5-di-tert-butylphenylsulfonamido)propanoate 
• 412964-66-0 3,5-di(tert-butyl)benzenesulfonamide 
• 1356133-19-1 3,5-di-tert-butyl-N-(pent-4-enyl)-benzenesulfonamide 
• 1380538-92-0 (S)-1-((3,5-di-tert-butylphenyl)sulfonyl)-2-(iodomethyl)pyrrolidine 
• 1416916-79-4 (S)-1-((3,5-di-tert-butylphenyl)sulfonyl)-2-(((2,2,6,6-tetramethylpiperidin-1-yl)oxy)methyl)indoline 
• 1416916-86-3 (S)-(1-((3,5-di-tert-butylphenyl)sulfonyl)indolin-2-yl)methanol 
• 1416916-81-8 (S)-1-((1-((3,5-di-tert-butylphenyl)sulfonyl)-4,4-dimethylpyrrolidin-2-yl)methoxy)-2,2,6,6-tetramethylpiperidine 
• 1416916-84-1 (S)-1-(1-((3,5-di-tert-butylphenyl)sulfonyl)-4,4-dimethylpyrrolidin-2-yl)methanol 
• 1416916-77-2 3,5-di-tert-butyl-N-(2,2-dimethylpent-4-en-1-yl)benzenesulfonamide 
• 1324003-84-0 3,5-di-t-butyl-N-(nona-1,8-dien-5-yl)benzenesulfonamide 
• 1324003-89-5 N-(2-allylpent-4-enyl)-3,5-di-tert-butylbenzenesulfonamide 

Relevant academic research and scientific papers

Amphipathic sulfonamidobenzamides mimicking small antimicrobial marine natural products; investigation of antibacterial and anti-biofilm activity against antibiotic resistant clinical isolates

There is an urgent need for novel antimicrobial agents to address the threat of bacterial resistance to modern society. We have used a structural motif found in antimicrobial marine hit compounds as a basis for synthesizing a library of antimicrobial sulf

Catalytic enantioselective alkene aminohalogenation/cyclization involving atom transfer

Problem solved: The title reaction was used for the synthesis of chiral 2-bromo, chloro, and iodomethyl indolines and 2-iodomethyl pyrrolidines (see scheme). Stereocenter formation is believed to occur by enantioselective cis aminocupration and C-X bond formation is believed to occur by atom transfer. The ultility of the products as versatile synthetic intermediates was demonstrated, as was a radical cascade cyclization sequence. Copyright

AMINOTETRAHYDROINDAZOLOACETIC ACIDS

The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, R1-R3 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manuf

MONOARYL AMINOTETRALINES

The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

Selective Sulfonylating Agents

A variety of bulky sulfonyl chlorides have been investigated as sulfonylating reagents for polyol systems in an endeavour to find a selective reagent that would also give rise to a reactive sulfonate ester group.