57892-11-2Relevant academic research and scientific papers
Copper-catalyzed [2+3]-annulation of N-H imines with vinyl azides: Access to polyaryl 2: H -imidazoles
Zhu, Zhongzhi,Lin, Hanze,Liang, Baihui,Huang, Junjie,Liang, Wanyi,Chen, Lu,Huang, Yubing,Chen, Xiuwen,Li, Yibiao
, p. 5621 - 5624 (2020/06/19)
A practical method for the synthesis of 2H-imidazoles via a [2+3] annulation of N-H imines with vinyl azides using a copper catalyst is developed. In this conversion, environmentally friendly oxygen is used as the sole oxidant and N2 and H2O are the only by-products. The catalytic transformation, operating under mild conditions, is operationally simple and is considered as a readily available catalytic system having good substrate and functional compatibility with high atom-efficiency without the need for additional ligands or additives.
A multi-substituted imidazole compounds and its synthetic method and application
-
Paragraph 0055-0062, (2019/05/22)
The present invention discloses a multi-substituted imidazole compounds and its synthetic method and application, its synthetic method for the synthesis route of: Wherein R1 Aryl, R2 Is aryl or alkyl, R3 Is aryl or alkyl;
Iron-Catalyzed Synthesis of 2H-Imidazoles from Oxime Acetates and Vinyl Azides under Redox-Neutral Conditions
Zhu, Zhongzhi,Tang, Xiaodong,Li, Jianxiao,Li, Xianwei,Wu, Wanqing,Deng, Guohua,Jiang, Huanfeng
, p. 1370 - 1373 (2017/03/23)
A novel and versatile method for the synthesis of 2H-imidazoles via iron-catalyzed [3 + 2] annulation from readily available oxime acetates with vinyl azides has been developed. This denitrogenative process involved N-O/N-N bond cleavages and two C-N bond formations to furnish 2,4-substituted 2H-imidazoles. This protocol was performed under mild reaction conditions and needed no additives or ligands. Furthermore, this is a green reaction involving oxime acetate as internal oxidant, acetic acid, and nitrogen as byproducts.
Photochemistry of Azole N-Oxides. Facile Photoisomerisation of 2H-Imidazole N-Oxides to 1,3-Diaza-6-oxabicyclohex-3-enes and Synthesis of a 1,3-Diaza-4,7-dioxatricyclo1,603,5>heptane
Gainsford, Graeme J.,Woolhouse, Anthony D.
, p. 803 - 809 (2007/10/02)
Ultraviolet irradiation of a series of 2H-imidazole N-oxides 2 has been shown to effect a clean isomerization to derivatives of the new ring system, 1,3-diaza-6-oxabicyclohex-3-ene, 7.Epoxidation of a representative 7 has given access to the hither
