57892-73-6 Usage
Uses
Used in Pharmaceutical Development:
Imidazo(1,2-a)pyrimidine-2-acetic acid is utilized as a lead compound in drug development for its potential therapeutic properties. Its chemical structure can be modified to enhance potency and selectivity, making it a versatile candidate for the treatment of a range of diseases.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Imidazo(1,2-a)pyrimidine-2-acetic acid serves as a subject of ongoing research to explore its biological activities and to understand its mechanisms of action. This research is crucial for identifying new therapeutic targets and developing novel drugs with improved efficacy and safety profiles.
Used in the Treatment of Various Diseases:
Given its potential pharmacological properties, Imidazo(1,2-a)pyrimidine-2-acetic acid is considered for use in the treatment of various diseases. Its application in this context is driven by the need to develop new and effective treatments that can address unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 57892-73-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,8,9 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 57892-73:
(7*5)+(6*7)+(5*8)+(4*9)+(3*2)+(2*7)+(1*3)=176
176 % 10 = 6
So 57892-73-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3O2/c12-7(13)4-6-5-11-3-1-2-9-8(11)10-6/h1-3,5H,4H2,(H,12,13)
57892-73-6Relevant academic research and scientific papers
Synthesis, crystal structures and spectral characterization of imidazo[1,2-a]pyrimidin-2-yl-acetic acid and related analog with imidazo[2,1-b]thiazole ring
Dylong, Agnieszka,Goldeman, Waldemar,Sowa, Micha?,?lepokura, Katarzyna,Drozdzewski, Piotr,Matczak-Jon, Ewa
, p. 153 - 163 (2016/04/06)
Imidazo[1,2-a]pyrimidin-2-yl-acetic acid (HIPM-2-ac) and its analog with imidazo[2,1-b]thiazole ring (HITZ-6-ac) were synthesized and structurally characterized by single-crystal X-ray diffraction corroborated with calculations of Hirshfeld surfaces, which provided detailed insight into intermolecular interactions constituting both crystals. The IR and Raman spectra of HIPM-2-ac and HITZ-6-ac were recorded and interpreted in details with the aid of Density Functional Theory (DFT) calculations and Potential Energy Distribution (PED) analysis of computed normal vibrations. Special attention was paid on hydroxyl and methylene groups involved in hydrogen bonds, which vibrations were monitored by H/D substitution. Recrystallization of parent compounds from deuterium oxide (D2O) solutions resulted in deuteration of their carboxylic OH groups and almost complete deuteration of HIPM-2-ac methylene group. The latter phenomenon is clearly reflected in the vibrational spectra and confirmed by 1H NMR experiments in solution.
