57898-80-3 Usage
Uses
Different sources of media describe the Uses of 57898-80-3 differently. You can refer to the following data:
1. The major metabolite of Acebutolol (A123800).
2. rac N-Desbutyroyl Acebutolol (Acebutolol EP Impurity D) is a major metabolite of Acebutolol (A123800).
Check Digit Verification of cas no
The CAS Registry Mumber 57898-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,8,9 and 8 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57898-80:
(7*5)+(6*7)+(5*8)+(4*9)+(3*8)+(2*8)+(1*0)=193
193 % 10 = 3
So 57898-80-3 is a valid CAS Registry Number.
57898-80-3Relevant articles and documents
A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production
Muta, Kyotaka,Fukami, Tatsuki,Nakajima, Miki
, p. 659 - 670 (2015)
Acebutolol, a β-adrenergic receptor-blocker, occasionally causes drug-induced lupus erythematosus (DILE). Acebutolol is mainly metabolized to diacetolol. Because metabolic activation has been considered to be related to acebutolol-induced toxicity, we sou