57917-63-2 Usage
Uses
Used in Pharmaceutical Industry:
1-Isopropyl Etodolac is used as an impurity in the synthesis of Etodolac, which is a nonsteroidal anti-inflammatory drug (NSAID). It is utilized for its anti-inflammatory and analgesic effects, helping to alleviate pain and reduce inflammation in various conditions.
Used in Oncology:
1-Isopropyl Etodolac may have potential use in the treatment of myeloma, a type of cancer that affects plasma cells in the bone marrow. Its exact role and mechanism of action in this context are still under investigation.
Used as COX-1/COX-2 Inhibitors:
1-Isopropyl Etodolac acts as an inhibitor of cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the production of prostaglandins, hormone-like substances that contribute to inflammation and pain. By inhibiting these enzymes, 1-Isopropyl Etodolac can help reduce inflammation and alleviate pain.
Used as β-catenin Inhibitors:
1-Isopropyl Etodolac may also have the potential to inhibit the Wnt/β-catenin signaling pathway, which plays a role in cell proliferation, differentiation, and migration. Inhibiting this pathway could have implications for the treatment of certain cancers and other diseases characterized by abnormal cell growth.
Check Digit Verification of cas no
The CAS Registry Mumber 57917-63-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,1 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 57917-63:
(7*5)+(6*7)+(5*9)+(4*1)+(3*7)+(2*6)+(1*3)=162
162 % 10 = 2
So 57917-63-2 is a valid CAS Registry Number.
57917-63-2Relevant academic research and scientific papers
SUBSTITUTED INDOLE DERIVATIVES
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Page/Page column 88, (2008/06/13)
Provided herein are indole derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.
