57930-20-8 Usage
Uses
Used in Pharmaceutical Industry:
Hydrazinecarboxamide, N-(1-Methylethyl)is used as an intermediate in the production of pharmaceutical drugs. It contributes to the synthesis of various medications, enhancing their efficacy and therapeutic potential.
Used in Agrochemical Industry:
In the agrochemical sector, Hydrazinecarboxamide, N-(1-Methylethyl)is utilized as an intermediate for the synthesis of herbicides and insecticides. Its incorporation aids in the development of effective crop protection agents, ensuring increased agricultural productivity and crop quality.
Used in Organic Synthesis:
Hydrazinecarboxamide, N-(1-Methylethyl)also serves as a reagent in organic synthesis. It is particularly instrumental in the development of new chemical compounds for a wide range of applications, including but not limited to research, material science, and specialty chemical production.
Check Digit Verification of cas no
The CAS Registry Mumber 57930-20-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,3 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57930-20:
(7*5)+(6*7)+(5*9)+(4*3)+(3*0)+(2*2)+(1*0)=138
138 % 10 = 8
So 57930-20-8 is a valid CAS Registry Number.
57930-20-8Relevant academic research and scientific papers
Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?
Adkison, Kim K.,Barrett, David G.,Deaton, David N.,Gampe, Robert T.,Hassell, Anne M.,Long, Stacey T.,McFadyen, Robert B.,Miller, Aaron B.,Miller, Larry R.,Payne, J. Alan,Shewchuk, Lisa M.,Wells-Knecht, Kevin J.,Willard Jr., Derril H.,Wright, Lois L.
, p. 978 - 983 (2007/10/03)
Starting from potent aldehyde inhibitors with poor drug properties, derivatization to semicarbazones led to the identification of a series of semicarbazone-based cathepsin K inhibitors with greater solubility and better pharmacokinetic profiles than their parent aldehydes. Furthermore, a representative semicarbazone inhibitor attenuated bone resorption in an ex vivo rat calvarial bone resorption model. However, based on enzyme inhibition comparisons at neutral pH, semicarbazone hydrolysis rates, and 13C NMR experiments, these semicarbazones probably function as prodrugs of aldehydes.
