57938-79-1 Usage
Classification
Beta-adrenergic antagonist
Medical uses
Antihypertensive, antiarrhythmic, prevention of angina, improvement of survival after a heart attack
Mechanism of action
Blocks the action of natural substances such as epinephrine on the heart and blood vessels
Form
Tablet for oral administration
Class of drugs
Beta-blockers
Importance of proper dosage
To ensure effectiveness and minimize risk of side effects
Check Digit Verification of cas no
The CAS Registry Mumber 57938-79-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,3 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 57938-79:
(7*5)+(6*7)+(5*9)+(4*3)+(3*8)+(2*7)+(1*9)=181
181 % 10 = 1
So 57938-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2O2/c10-9(13)6-11-5-7-3-1-2-4-8(7)12/h1-4,11-12H,5-6H2,(H2,10,13)
57938-79-1Relevant articles and documents
Radioisotopic and synthetic studies related to caroxazone metabolism in man
Bernardi,Coda,Nicolella,Vicario,Gioia,Minghetti,Vigevani,Arcamone
, p. 1412 - 1416 (2007/10/10)
Labelled 2-oxo-2H-1,3-benzoxazine-3(4H)-acetamide (caroxazone), has been synthesized by condensing N-(2-hydroxylbenzyl)glycinamide with 14C phosgene. Metabolic studies were performed administering the labelled drug to man and recovering metabolites from the urines. Beside the unchanged drug, five metabolites were identified and confirmed by synthesis, namely (3,4-dihdydro-3-carboxamidomethyl-2-oxo-2H-1,3-benzoxazin-4-yl)urea, N-carboxamidomethyl o-hydroxymethylphenyl carbamate, 4-methoxy-2-oxo-2H-1,3-benzoxazine-3(4H)acetamide, 2-oxo-2H-1,3-benzoxazine-3(4H)acetic acid, and 4-hydroxy-2-oxo-2H-1,3-benzoxazine-3(4H)acetamide.
