57947-00-9 Usage
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 7119554 is used as a key intermediate in the synthesis of Diaminopyrimidines for their application as BRD4 and kinase inhibitors. These inhibitors play a crucial role in the treatment of cancer by targeting specific proteins and enzymes involved in cancer cell growth and proliferation.
Used in Cancer Treatment:
CHEMBRDG-BB 7119554 contributes to the development of Diaminopyrimidines, which are employed as inhibitors in cancer treatment. By targeting BRD4 and various kinases, these inhibitors can effectively suppress the growth and progression of cancer cells, offering a promising therapeutic approach for patients suffering from various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 57947-00-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,4 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 57947-00:
(7*5)+(6*7)+(5*9)+(4*4)+(3*7)+(2*0)+(1*0)=159
159 % 10 = 9
So 57947-00-9 is a valid CAS Registry Number.
57947-00-9Relevant academic research and scientific papers
BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS
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Page/Page column 233; 237, (2017/05/02)
Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I through IV.
POTENT DUAL BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS
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Page/Page column 122; 125-126, (2016/04/26)
Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV.
