57948-41-1

Basic information

• Product Name: 3-BROMOIMIDAZO[1,2-A]PYRAZINE
• Synonyms: 3-BROMOIMIDAZO[1,2-A]PYRAZINE;IMidazo[1,2-a]pyrazine, 3-broMo-;3-Bromoimidazo[1,2-a]pyrazine3-Bromoimidazo[1,2-a]pyrazine
• CAS NO: 57948-41-1
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 198.02
• Product Categories: Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrazines;PyrazinesHeterocyclic Building Blocks
• Mol File: 57948-41-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 191-196 °C
• Appearance: /
• Density: 1.89±0.1 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.751
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 1.35±0.30(Predicted)
• CAS DataBase Reference: 3-BROMOIMIDAZO[1,2-A]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMOIMIDAZO[1,2-A]PYRAZINE(57948-41-1)
• EPA Substance Registry System: 3-BROMOIMIDAZO[1,2-A]PYRAZINE(57948-41-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 57948-41-1(Hazardous Substances Data)

Usage

General Description

3-Bromoimidazo[1,2-a]pyrazine is a chemical compound that belongs to the class of organic compounds known as imidazo[1,2-a]pyrazines. These are polycyclic aromatic compounds containing an imidazo[1,2-a]pyrazine moiety, which consists of a pyrazine fused to an imidazole. As an organobromine compound, it contains bromine atoms bonded to carbon atoms. Specific properties such as melting point, boiling point, or potential applications for this compound may depend on its molecular structure and any additional functional groups that may be present. However, specific information about this compound is not widely available in the literature, suggesting it may not have significant known industrial or pharmaceutical applications.

InChI:InChI=1/C6H4BrN3/c7-5-3-9-6-4-8-1-2-10(5)6/h1-4H

Upstream product

• 274-79-3 imidazo[1,2-a]pyrazine 

Relevant articles and documents

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Synthesis of imidazo[1,2-a]pyrazine derivatives with uterine-relaxing, antibronchospastic, and cardiac-stimulating properties

A series of imidazo[1,2-a]pyrazine derivatives was synthesized by condensation of α-halogenocarbonyl compounds and aminopyrazines. Various compounds resulted from competitive reactions or reagent isomerization and demonstrated in vitro uterine-relaxing and in vivo antibronchospastic activities. On isolated atria, 5-bromoimidazo[1,2-a]pyrazine showed positive chronotropic and inotropic properties; the latter was associated with an increase in the cyclic AMP tissue concentration. Potentiation of the isoproterenol positive inotropic effect of 5-bromoimidazo[1,2-a]pyrazine and the lack of blockade of the 5-bromoimidazo[1,2-a]pyrazine positive inotropic effect by propranolol suggested phosphodiesterase-inhibiting properties.