579488-90-7Relevant articles and documents
Amine-promoted cyclocondensation of highly substituted aromatic nitrile oxides with diketones
Bode, Jeffrey W.,Hachisu, Yoshifumi,Matsuura, Tomoo,Suzuki, Keisuke
, p. 3555 - 3558 (2003)
Base-promoted cyclocondensation of hindered nitrile oxides and cyclic diketones affords highly functionalized, sterically-encumbered isoxazole products in good yield. The mild reaction conditions (NEt3, EtOH) are tolerant to a wide variety of f