579491-01-3Relevant academic research and scientific papers
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides
Sperlinga, Emanuela,Kosson, Piotr,Urbanczyk-Lipkowska, Zofia,Ronsisvalle, Giuseppe,Carr, Daniel B.,Lipkowski, Andrzej W.
, p. 2467 - 2469 (2005)
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (6Htc) has been proposed as a rigid mimic of tyrosine conformation in opioid ligand-receptor complex. The significant receptor binding to mu and delta opioid receptors of respective analogues of
