579516-15-7

Upstream product

• 122-80-5 N-acetyl-p-phenylenediamine 
• 104-04-1 N-(4-Nitrophenyl)acetamide 
• 100-01-6 4-nitro-aniline 
• 579516-14-6 N-(4-(2-chloropyrimidin-4-ylamino)phenyl)acetamide 
• 74-88-4 methyl iodide 

Downstream Products

• 862264-34-4 N-(4-{[2-(3-methanesulfonylmethyl-phenylamino)-pyrimidin-4-yl]-methyl-amino}-phenyl)-acetamide 
• 579516-12-4 1-(4-{[2-(3-methanesulfonylmethyl-phenylamino)-pyrimidin-4-yl]-methyl-amino}-phenyl)-3-phenyl-thiourea 
• 579516-20-4 N⁴-(4-amino-phenyl)-N²-(3-methanesulfonylmethyl-phenyl)-N⁴-methyl-pyrimidine-2,4-diamine 

Relevant academic research and scientific papers

METHODS FOR INHIBITING NECROPTOSIS

The present invention relates to methods for inhibiting necroptosis; screening methods for identifying compounds which inhibit necroptosis; and compounds for the inhibition of necroptosis, which may be useful in the treatment of conditions associated with deregulated necroptosis.

Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase

A series of dianilinopyrimidineureas demonstrate potency as VEGFR2 kinase inhibitors.