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57964-81-5

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57964-81-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 57964-81-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,6 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 57964-81:
(7*5)+(6*7)+(5*9)+(4*6)+(3*4)+(2*8)+(1*1)=175
175 % 10 = 5
So 57964-81-5 is a valid CAS Registry Number.

57964-81-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-benzyl-1,2,4-triazole-3,5-dione

1.2 Other means of identification

Product number -
Other names 4-benzyl-1,2,4-triazoline-3,5-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57964-81-5 SDS

57964-81-5Relevant articles and documents

Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives

Alakurtti, Sami,Heiska, Tuomo,Kiriazis, Alexandros,Sacerdoti-Sierra, Nina,Jaffe, Charles L.,Yli-Kauhaluoma, Jari

experimental part, p. 1573 - 1582 (2010/05/02)

Betulin, a naturally occurring abundant triterpene is converted in four steps to 3,28-di-O-acetyllupa-12,18-diene. When various 4-substituted urazoles were oxidized to the corresponding urazines with iodobenzene diacetate in the presence of 3,28-di-O-acetyllupa-12,18-diene, new heterocyclic betulin derivatives were produced. These betulin derivatives were examined in a microplate assay at 50 μM for their ability to inhibit the growth of Leishmania donovani axenic amastigotes, a species that causes the fatal visceral leishmaniasis. GI50 (concentration for 50% growth inhibition) values of the most effective compounds were determined and their cytotoxicity on the human macrophage cell line THP-1 evaluated. The anti-leishmanial activity on L. donovani amastigotes growing in macrophages was also examined. The heterocycloadduct between 3,28-di-O-acetyllupa-12,18-diene and 4-methylurazine was the most effective derivative with an GI50 = 8.9 μM against L. donovani amastigotes.

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