57969-26-3Relevant academic research and scientific papers
Structural diversity and similar bioactivity in synthetic bicyclononanes
Luna, Liliana E.,Forastieri, Pamela S.,Marchiaro, Patricia,Limansky, Adriana,Cravero, Raquel M.
, p. 404 - 414 (2016)
Simple syntheses of diverse bicyclo[3.3.1]nonanes and related compounds as the minimal substructure of bioactive natural products via Michael, aldol, and alkylation reactions from diketones are described herein. The structures of the synthesized compounds
Method for acid catalysis of 1,3-cyclodiketone isopentenylation reaction
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Paragraph 0044; 0055-0057; 0060, (2021/06/09)
The invention relates to chemically selective isopentenylation reaction of 1,3-cyclodiketone with different sources of isopentenyl groups. Specifically, 1,3-cyclohexanedione and isoprene are taken as raw materials, and under the condition of solid acid catalysis, an isopentenylation reaction on C can be realized to obtain [3+3] cyclized 5-chromenone derivatives; and isopentenylation products on oxygen atoms can be obtained during catalysis by Lewis acid. The method of the invention has the following advantages: isoprene is a green bulk chemical, is simple and easy to obtain, and is low in price; 1,3-cyclodiketone is cheap in price, easy to obtain and stable in property; the reaction with the chemical selectivity can be performed only by using different isopentenyl sources in the presence of a catalytic amount of the solid acid or the Lewis acid; operation is simple, atom economy is high, and the obtained products have potential application value.
Acid-catalyzed chemoselective C- and O- prenylation of cyclic 1,3-diketones
Chen, Qing-An,Cong, Yu-Feng,He, Gu-Cheng,Hu, Yan-Cheng,Ji, Ding-Wei,Li, Ying,Zhang, Wei-Song
, p. 1401 - 1409 (2020/04/30)
The chemoselective C- and O-prenylation of cyclic 1,3-diketones was achieved by tuning the prenyl source and catalyst. In the presence of the solid acid Nafion, the coupling of 1,3-cyclohexanediones with isoprene gave C-prenylated 5-chromenones. Alternati
