580-47-2

Usage

Chemical Family

Porphyrin
A macrocyclic organic compound with a ring structure based on four pyrrole subunits interconnected by methine bridges.

Molecular Structure

Modified Porphyrin
Contains alterations to the standard porphyrin structure, with added ethyl and methyl groups.

Substituents

Four Ethyl Groups and Four Methyl Groups
Ethyl and methyl groups are attached to the pyrrole rings, contributing to its unique properties.

Role in Living Organisms

Cofactors in Enzymatic Reactions
Porphyrins play an essential role in biological processes, aiding in numerous enzymatic reactions within living organisms.

Applications

Photodynamic Therapy and Artificial Enzymes
The compound has potential uses in medical treatments like photodynamic therapy and as a molecular scaffold for constructing artificial enzymes.

Potential Fields of Application

Materials Science, Medicine, and Biochemistry
Due to its unique structural and electronic properties, the compound can be utilized in various scientific fields for different purposes.

Unique Properties

Structural and Electronic
The combination of ethyl and methyl groups, as well as its modified porphyrin structure, give the compound distinct properties that make it valuable in research and applications.

InChI:InChI=1/C32H38N4/c1-9-21-17(5)25-13-26-18(6)22(10-2)30(34-26)15-28-20(8)24(12-4)32(36-28)16-31-23(11-3)19(7)27(35-31)14-29(21)33-25/h13-16,33,36H,9-12H2,1-8H3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-

Upstream product

• 107287-36-5 1,4,6,7,8'-pentaethyl-1',2,3,5,8-pentamethyl-a,c-biladiene dihydrobromide 
• 112452-37-6 3,5-diethyl-4-methyl-pyrrole-2-carbaldehyde 
• 32948-29-1 benzyl 3,5-diethyl-4-methylpyrrole-2-carboxylate 
• 131881-75-9 3,3'-dimethyl-4,4'-diethyldipyrrylmethane 
• 2199-47-5 ethyl 3,5-dimethyl-4-ethylpyrrole-2-carboxylate 
• 6250-80-2 4-ethyl-3,5-dimethylpyrrole-2-carbaldehyde 
• 517-22-6 2,4-dimethyl-3-ethyl-pyrrole 
• 872614-99-8 dibutyl 4,4'-diethyl-3,3'-dimethyl-2,2'-dipyrrylmethane-5,5'-dicarboxylate 
• 872614-96-5 butyl 3-ethyl-4-methylpyrrole-2-carboxylate 
• 112452-53-6 1,3,6-triethyl-2,4,5,6'-tetramethyltripyrrene-1'-carboxylate hydrobromide 
• 112452-36-5 3,5-Diethyl-4-methyl-1H-pyrrole-2-carboxylic acid 
• 3750-36-5 benzyl 5-(acetoxymethyl)-4-ethyl-3-methyl-1H-pyrrole-2-carboxylate 
• 66145-66-2 Bis-(3-aethyl-5-brom-4-methyl-pyrrol-2-yl)-methinium-bromid 
• 52853-18-6 N,N-diethyl(methylene)ammonium chloride 

Relevant academic research and scientific papers

Syntheses of per-15N labeled etioporphyrins I-IV and a related tetrahydrobenzoporphyrin for applications in organic geochemistry and vibrational spectroscopy

Nitrogen-15 labeled pyrroles have been prepared from commercially available 15N glycine or sodium nitrite using the Barton-Zard, Knorr, and Kleinspehn approaches. These pyrroles were used as intermediates in the synthesis of per-15N labeled porphyrins needed for the analysis and assignment of vibrational spectra for sedimentary porphyrins. Etioporphyrin-I was prepared via pyrromethene intermediates, while etioporphyrins II-V and a related tetrahydrobenzoporphyrin were synthesized via stepwise routes involving the copper(II) mediated cyclization of a,c-biladienes as the key step. Detailed analyses of both the proton and carbon-13 NMR spectra provide nitrogen-15 coupling constants for these important structures.

Synthesis and investigation of glycosylated mono- and diarylporphyrins for photodynamic therapy

The synthesis of a diaryl substituted porphyrin bearing a galactosyl and a cholesteryloxy substituent and of a galactosyl substituted monoaryl porphyrin is described. The spectroscopic and aggregation properties of both compounds were investigated. The ga

Cyclotetramerization of modified Knorr pyrroles into porphyrins. A reinvestigation.

The tetramerization of 3-ethyl-4-methyl-5-(methoxymethyl)pyrrole derivatives into is reinvestigated.This study demonstaretes that in most cases the starting material were misidentified and that, under controlled conditions, the pyrrole redistribution reac

Cyclizations of Terminally Substituted a,c-Biladiene Salts to give meso-Substituted Porphyrins

Cyclizations of 1',8'-disubstituted a,c-biladiene salts using copper(II) salts afford the corresponding meso-substituted porphyrins (after removal of copper) along with smaller amounts of the corresponding meso-unsubstituted analogues.For example, the a,c

CYCLIZATION OF SOME TERMINALLY SUBSTITUTED α,β-BILADIENES

Several examples of 1',8'-disubstituted a,c-biladiene salt cyclizations, using copper(II) or iodine/bromine in hot o-dichlorobenzene, to give meso-substituted porphyrins are described.