58000-14-9Relevant academic research and scientific papers
Deaminative and decarboxylative catalytic alkylation of amino acids with ketones
Kalutharage, Nishantha,Yi, Chae S.
, p. 13651 - 13655 (2013)
It cuts two ways: The cationic [Ru-H] complex catalyzes selective coupling of α- and β-amino acids with ketones to form α-alkylated ketone products. The reaction involves C-C and C-N bond cleavage which result in regio- and stereoselective alkylation using amino acids. A broad substrate scope and high functional-group tolerance is demonstrated. Copyright
