58005-18-8 Usage
Uses
Used in Pharmaceutical Industry:
N-isopropyltropinium is used as an impurity in the production of Ipratropium, which is a bronchodilator medication. It is utilized for its anticholinergic properties to treat patients with chronic bronchitis, cardiac obstructive pulmonary disease (COPD), and asthma. The application of N-isopropyltropinium in this context is due to its role in the synthesis and formulation of Ipratropium, which helps in managing respiratory conditions by relaxing the smooth muscles in the airways.
Check Digit Verification of cas no
The CAS Registry Mumber 58005-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,0,0 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 58005-18:
(7*5)+(6*8)+(5*0)+(4*0)+(3*5)+(2*1)+(1*8)=108
108 % 10 = 8
So 58005-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H22NO.BrH/c1-8(2)12(3)9-4-5-10(12)7-11(13)6-9;/h8-11,13H,4-7H2,1-3H3;1H/q+1;/p-1
58005-18-8Relevant academic research and scientific papers
A new method for preparing ipratropine (by machine translation)
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Paragraph 0040, (2017/09/02)
The invention discloses a ipratropine preparation method, comprises the following steps: benzene acetic acid methyl ester (III) as the starting material, the reaction process for preparing substituted α - formyl benzene acetic acid methyl ester (IV); tropine is mellow with methyl bromide reaction to prepare the compound (II); compound (II) with a compound (IV) reaction of compounds (V), compound (V) reduction process of preparing ipratropine anhydride, through the refining preparation ipratropine (VII), the method is simple in operation, high safety, low cost, is more suitable for industrial production. (by machine translation)
Synthesis of ipratropium bromide-related compounds
Tsyskovskaia, Irina,Kandil, Mustapha,Beaumier, Yves
, p. 439 - 446 (2007/10/03)
Synthesis of ipratropium bromide metabolites is described. Copyright Taylor & Francis Group, LLC.
