5803-73-6Relevant academic research and scientific papers
Sulfur-containing heterocyclic compounds useful for the treatment of osteoporosis, and their production
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, (2008/06/13)
The present invention provides a sulfur-containing heterocyclic compound of the formula (I) STR1 wherein ring A is a benzene ring which may be substituted; R is a hydrogen atom or a hydrocarbon group which may be substituted; B is a carboxyl group which may be esterified or amidated; X is --CH(OH)-- or --CO--; k is 0 or 1; and k' is 0, 1 or 2 or a pharmaceutically acceptable salt thereof. Also, it provides a process for producing the compound (I) or a salt thereof and a pharmaceutical preparation for use in the treatment of osteoporosis comprising the compound (I) or salt thereof. The compounds (I) and salts thereof show excellent bone resorption inhibitory activity.
Thiazolidine derivatives and production thereof
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, (2008/06/13)
A new thiazolidine derivative of the formula: STR1 wherein n stands for an integer of 3 to 6 and salts thereof show strong aldose reductase inhibition and are useful for prophylaxis or therapy of diabetic cataracts and diabetic neuropathy in mammals.
