58065-21-7 Usage
Uses
Used in Oncology:
Pixantrone is utilized as an antineoplastic agent for the treatment of various types of cancers, such as non-Hodgkin lymphoma and leukemia. Its unique mechanism of action as a DNA intercalator and topoisomerase II inhibitor allows it to effectively inhibit DNA replication and transcription in cancer cells, leading to the suppression of tumor growth and progression.
Used in Cardiotoxicity Reduction:
Pixantrone is used as a less cardiotoxic alternative to other anthracycline-based chemotherapeutic agents. Its reduced cardiotoxicity profile makes it a valuable candidate for cancer treatment, particularly for patients who may be at higher risk of developing cardiac complications from traditional chemotherapy.
Used in Combination Therapy:
Pixantrone is being investigated for its potential use in combination therapy regimens. By combining pixantrone with other anticancer agents, researchers aim to improve the overall efficacy of cancer treatment while reducing the likelihood of adverse effects. This approach may lead to more personalized and effective treatment strategies for patients with various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 58065-21-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,0,6 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 58065-21:
(7*5)+(6*8)+(5*0)+(4*6)+(3*5)+(2*2)+(1*1)=127
127 % 10 = 7
So 58065-21-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13ClN2O3S/c17-11-12(18)9-10(13(19)16(11)23-6-5-20)15(22)8-4-2-1-3-7(8)14(9)21/h1-4,20H,5-6,18-19H2
