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2-Aminoacridine, with the molecular formula C13H10N2, is an organic chemical compound belonging to the heterocyclic amine class. Characterized by its fluorescent yellow-green color, it is widely recognized for its applications as a dye and in the synthesis of pharmaceuticals, notably antitumor and antiviral drugs. Its potential in cancer treatment, as a DNA intercalating agent, and its ability to inhibit topoisomerase II enzymes make it a subject of ongoing research. Additionally, it is utilized in the production of fluorescent dyes for microscopy and as a component in DNA staining kits. However, due to its hazardous nature, including its mutagenic and potential carcinogenic properties, strict safety measures are essential during its handling and use.

581-28-2

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581-28-2 Usage

Uses

Used in Pharmaceutical Industry:
2-Aminoacridine is used as a key intermediate in the synthesis of pharmaceuticals for its potential therapeutic effects in treating cancer and viral infections. Its ability to intercalate with DNA and inhibit topoisomerase II enzymes contributes to its role in developing antitumor and antiviral drugs.
Used in Research Applications:
In the field of research, 2-Aminoacridine serves as a DNA intercalating agent, facilitating studies on DNA structure, function, and interactions with other molecules. Its fluorescent properties also make it a valuable tool in microscopy for visualizing cellular components and processes.
Used in Diagnostics and Staining:
2-Aminoacridine is used as a component in DNA staining kits, where its fluorescent characteristics aid in the detection and analysis of DNA in various diagnostic applications.
Used in Manufacturing of Fluorescent Dyes:
2-AMINOACRIDINE is utilized in the production of fluorescent dyes for microscopy, enabling the visualization of specific structures within cells and tissues with enhanced contrast and detail.

Check Digit Verification of cas no

The CAS Registry Mumber 581-28-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 581-28:
(5*5)+(4*8)+(3*1)+(2*2)+(1*8)=72
72 % 10 = 2
So 581-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H10N2/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)15-13/h1-8H,14H2

581-28-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name acridin-2-amine

1.2 Other means of identification

Product number -
Other names 2-Acridinamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:581-28-2 SDS

581-28-2Relevant academic research and scientific papers

Preparation of esters of phosphorus acids

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, (2008/06/13)

Esters of phosphorus acids are prepared by an improved process whereby aromatic alcohols and phosphorus halides are reacted at specified temperatures in the presence of amine catalysts thereby providing high yields of substantially pure esters and allowing preparation of selected halogen-containing mono- and di-esters of phosphorus acids wherein halogen is directly bonded to phosphorus having substantially no side reactant contamination. The phosphorus esters are useful as intermediates in the preparation of plasticizers, oil additives and functional fluids.

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