581103-92-6

Basic information

• Product Name: 4-amino-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one
• Synonyms: 4-amino-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one
• CAS NO: 581103-92-6
• Molecular Weight: 599.018
• Mol File: 581103-92-6.mol

Chemical Properties

• CAS DataBase Reference: 4-amino-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one(581103-92-6)
• EPA Substance Registry System: 4-amino-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one(581103-92-6)

Safety Data

• Hazardous Substances Data: 581103-92-6(Hazardous Substances Data)

Upstream product

• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 

Downstream Products

• 581104-43-0 2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-6-(4-chlorobenzyl)-3-thioxo-2,3-dihydro-1,2,4-triazin-5(4H)-one 

Relevant articles and documents

Selective synthesis and reactions of 6-substituted-2-β-galactosyl-1,2,4-triazines of potential anticancer activity

Selective synthesis and reactions of different 6-substituted-2-β-D-galactosyl-3-thioxo-2,3-dihydro-1,2, 4-triazin-5(4H)-ones using the developed amino or aryl protecting group strategy were investigated. Primary human anticancer screening of twelve selected compounds (in vitro) resulted in an active compound against both MCF7 (Breast) and SF-268(CNS) cell lines.