58112-14-4Relevant academic research and scientific papers
An Efficient Greener Approach for N-acylation of Amines in Water Using Benzotriazole Chemistry
Ibrahim, Tarek S.,Seliem, Israa A.,Panda, Siva S.,Al-Mahmoudy, Amany M.M.,Abdel-Samii, Zakaria K.M.,Alhakamy, Nabil A.,Asfour, Hani Z.,Elagawany, Mohamed
, (2020/06/17)
A straightforward, mild and cost-efficient synthesis of various arylamides in water was accomplished using versatile benzotriazole chemistry. Acylation of various amines was achieved in water at room temperature as well as under microwave irradiation. The developed protocol unfolds the synthesis of amino acid aryl amides, drug conjugates and benzimidazoles. The environmentally friendly synthesis, short reaction time, simple workup, high yields, mild conditions and free of racemization are the key advantages of this protocol.
PAPAIN-CATALYZED SYNTHESIS OF 2-NAPHTHYLAMIDES OF N-ACYLAMINO ACIDS AND DIPEPTIDES
Cerovsky, Vaclav,Saks, Tatana,Jost, Karel
, p. 2309 - 2316 (2007/10/02)
2-Naphthylamides of several N-acylamino acids were prepared by papain-catalyzed condensation reaction in acidic medium.Under the same conditions, papain catalyzed the synthesis of peptide bond between benzyloxycarbonylglycine and phenylalanine 2-naphthyla
