58113-24-9

Upstream product

• 108-85-0 1-bromocyclohexane 
• 25519-79-3 1-(4-benzoylpiperidin-1-yl)ethanone 

Downstream Products

• 64061-56-9 α-cyclohexyl-α-phenyl-4-piperidinemethanol 
• 60284-78-8 1-[4-[3-[4-(Cyclohexylhydroxyphenylmethyl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone hydrochloride 

Relevant academic research and scientific papers

Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-piperidines and Structurally Related Compounds

A series of 4-(diarylhydroxymethyl)-1-piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1--1-piperidinyl>propoxy>-3-methoxyphenyl>ethanone (1, AHR-5333) was more potent than oxatomide and terfenadine in this assay.

1-Substituted-4-benzylpiperidines

Novel 1-substituted-4-benzylpiperidines having α-substituents on the 4-benzyl moiety useful as antiinflammatory agents, sedatives, and tranquilizers are represented by the formula SPC1 Wherein R represents acetyl, aryloxyloweralkyl, aroylloweralkylcarbamo