58125-69-2

Basic information

• Product Name: ethyl 2-(4-methoxyphenyl)acetimidate hydrochloride
• Synonyms: ethyl 2-(4-methoxyphenyl)acetimidate hydrochloride
• CAS NO: 58125-69-2
• Molecular Weight: 229.707
• Mol File: 58125-69-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-methoxyphenyl)acetimidate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-methoxyphenyl)acetimidate hydrochloride(58125-69-2)
• EPA Substance Registry System: ethyl 2-(4-methoxyphenyl)acetimidate hydrochloride(58125-69-2)

Safety Data

• Hazardous Substances Data: 58125-69-2(Hazardous Substances Data)

Upstream product

• 104-47-2 p-methoxybenzylnitrile 
• 64-17-5 ethanol 

Downstream Products

• 58125-68-1 2-(4-Methoxy-benzyl)-3H-imidazo[4,5-b]pyridine 
• 139097-22-6 N-<(4-Methoxyphenyl)acetyl>fumarsaeure-amid-methylester 
• 141246-09-5 3-[2-(4-Methoxy-benzyl)-5-methyl-benzoimidazol-1-yl]-butyric acid 
• 35321-38-1 3-[2-(4-Methoxy-benzyl)-benzoimidazol-1-yl]-butyric acid 
• 76751-79-6 N-[2'-(2-Dimethylamino-ethylamino)-biphenyl-2-yl]-2-(4-methoxy-phenyl)-acetamide 
• 76751-80-9 N-[2'-(3-Dimethylamino-propylamino)-biphenyl-2-yl]-2-(4-methoxy-phenyl)-acetamide 
• 57687-95-3 N-(4-Methoxyphenylacetyl)fumardiamid 
• 92434-94-1 5-chloro-2-(4-methoxybenzyl)-1H-benzo[d]imidazole 
• 53464-42-9 p-Methoxy-2-benzyl-5-trifluormethyl-benzimidazol 

Relevant articles and documents

Colchicine derivatives, and preparation method and medical application thereof

The invention specifically relates to colchicine derivatives (I) as described in the specification and a preparation method thereof, and pharmaceutical compositions containing the colchicine derivatives, belonging to the field of medicinal chemistry. The results of pharmacodynamic experiments prove that the colchicine derivatives of the invention have treatment effect on lumbar disc herniation andliver fibrosis.

Copper(II)-Catalyzed Benzylic C(sp3)-H Aerobic Oxidation of (Hetero)Aryl Acetimidates: Synthesis of Aryl-α-ketoesters

A straightforward method is developed in this paper for the synthesis of α-ketoesters through copper-catalyzed aerobic oxidation of (hetero)aryl acetimidates using molecular oxygen as a sustainable oxidant. The reaction represents the first example of the direct synthesis of aryl-α-ketoesters from arylacetimidates through the aerobic oxidation of a benzylic C(sp3)-H (CO) bond in moderate to good yield. This transformation occurs under mild reaction conditions with a wide range of substrates and utilizes a readily available oxidant and catalyst. The synthetic utility of this transformation is demonstrated through scaled-up synthesis. A plausible reaction mechanism is also proposed.

[(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders

The present invention relates to N-pyridylamidine and N-pyridylguanidine derivatives of general formula (I) in which: Ar1 is an optionally substituted phenyl ring; Ar2 is an optionally substituted phenyl ring; R1 is hydrogen or C1-4 alkyl; R2 is hydrogen or C1-4 alkyl; R3 is hydrogen or C1-4 alkyl; R4 is hydrogen, halogen, C1-6 alkyl or C1-6 alkoxy; X is CH2 or NR5, and R5 is hydrogen or C1-4 alkyl, and the salts thereof, and their use in therapy as gastric acid secretion inhibitors.