58138-72-0

Upstream product

• 2612-02-4 5-methoxysalicylic acid 
• 17336-15-1 5-methoxyaspirin 

Downstream Products

• 175649-99-7 2-<1-(2-acetoxy-5-methoxybenzoyl)-1H-imidazol-2-yl>-1-(2-acetoxy-5-methoxyphenyl)vinyl 2-acetoxy-5-methoxybenzoate 
• 1415566-87-8 C₁₃H₁₁N₃O₆S 
• 1237519-33-3 4-(furan-2-yl)-2-(2-hydroxy-5-methoxybenzamido)benzoic acid 
• 1237519-38-8 methyl 2-(2-acetoxy-5-methoxybenzamido)-4-(2-((tert-butoxycarbonyl)(methyl)amino)phenyl)benzoate 
• 1237519-32-2 methyl 2-(2-acetoxy-5-methoxybenzamido)-4-(furan-2-yl)benzoate 
• 1237514-84-9 2-(2-hydroxy-5-methoxybenzamido)-4-(2-(methylamino)phenyl)benzoic acid 
• 1237514-81-6 sodium 4-(furan-2-yl)-2-(2-hydroxy-5-methoxybenzamido)benzoate 
• 110672-17-8 6-Methoxy-3-(1-methyl-1H-imidazol-2-yl)-2-phenyl-4H-1-benzopyran-4-one 
• 110672-14-5 1-(2-hydroxy-5-methoxyphenyl)-2-(1-methyl-1H-imidazol-2-yl)ethenol 
• 367526-61-2 diethyl 2-{hydroxy[5-methoxy-2-(acetoxy)phenyl]methylene}malonate 
• 279215-20-2 N-tert-butyl-2,N-dihydroxy-5-methoxy-benzamide 

Relevant academic research and scientific papers

Synthesis of 2-Fluoro-1,4-benzoxazines and 2-Fluoro-1,4-benzoxazepin-5-ones by Exploring the Nucleophilic Vinylic Substitution (SNV) Reaction of gem-Difluoroenamides

N-Benzoyl β,β-difluoroenamides and N-benzoyl fluoroynamides are novel structural units which have been explored as precursors in heterocyclic synthesis. The presence of two fluorine atoms at the β-position of the enamide moiety endows unique electrophilic

Development of 5-nitrothiazole derivatives: Identification of leads against both replicative and latent Mycobacterium tuberculosis

Twenty eight 5-nitrothiazole derivatives were synthesized and evaluated for in vitro activities against Mycobacterium tuberculosis (MTB), cytotoxicity against HEK 293T. Among the compounds, 5-nitro-N-(5-nitrothiazol-2-yl)furan-2- carboxamide (20) was found to be the most active compound in vitro with MICs of 5.48 μM against log-phase culture of MTB and also non-toxic up to 100 μM.

N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An N-acyl anthranilic acid derivative represented by general formula (1) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl group or the like; R2 represents a hydrogen atom or the like; R3 represents an optionally substituted aryl group or the like; X1 represents a carbonyl group; X2 represents a bonding hand; X3 represents a bonding hand; X4 represents a bonding hand or the like; and A represents an optionally substituted phenyl group or the like.)

N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An N-acyl anthranilic acid derivative represented by general formula (1) or a salt thereof is useful for prevention or treatment of diseases associated with excessive production of collagen. (In the formula, R1 represents a carboxyl group or th

Compounds and compositions for delivering active agents

Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or lipid. Methods of administration, including oral administration, and preparation are provided as well.

4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

The structure-based design of potent and selective urokinase-type plasminogen activator (uPA) inhibitors with 4-aminoarylamidine or 4-aminoarylguanidine S1 binding groups, is described.

A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids

2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.

The first general synthesis of N-substituted 1,2-benzisoxazolin-3-ones

A convenient synthesis of the title compounds has been developed. Key synthetic steps include: (1) conversion of the readily available salicylic acid derivatives to the corresponding N-substituted salicylhydroxamic acids; (2) cyclization of the hydroxamic acids under Mitsunobu conditions to give the title compounds. (C) 2000 Elsevier Science Ltd.

Substituted 2-amino chromones and process for the preparation thereof

This invention relates to substituted 2-amino chromones of the general structure I: SPC1 wherein R1, R2, R3, and R4 may be hydrogen, hydroxy, lower alkyl or lower alkoxy of 1-6 carbon atoms, halogen such as chloro or bromo, or aryl such as phenyl, and X may be cyano or carboxamido. Two novel procedures for preparing substituted 2-amino chromones having the Formula I, starting with salicylic acid or substituted salicylic acid, are described. The compounds of this invention are active in the prevention of allergic and asthmatic reactions in mammals.