58143-72-9

Upstream product

• 58143-70-7 4-Methyl-2-phenyl-4-pentennitril 
• 76403-21-9 (±)-4-methyl-2-phenyl-4-pentenoic acid 
• 103-82-2 phenylacetic acid 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 58143-97-8 4-(2-Methyl-allyl)-4-phenyl-cyclohex-2-enol 
• 58143-73-0 4-(2'-Methylallyl)-4-phenylcyclohex-2-en-1-on 

Relevant academic research and scientific papers

Dynamic Kinetic Resolution of Aldehydes by Hydroacylation

We report a dynamic kinetic resolution (DKR) of chiral 4-pentenals by olefin hydroacylation. A primary amine racemizes the aldehyde substrate via enamine formation and hydrolysis. Then, a cationic rhodium catalyst promotes hydroacylation to generate α,γ-disubstituted cyclopentanones with high enantio- and diastereoselectivities.

Platinum(IV)-Catalyzed Synthesis of Unsymmetrical Polysubstituted Benzenes via Intramolecular Cycloaromatization Reaction

A one-pot synthesis of polysubstituted benzene derivatives was achieved via a platinum(IV)-catalyzed intramolecular cycloaromatization reaction. The reaction proceeds via a tandem skeletal rearrangment, dehydration and double bond isomerization, which proved to be very useful for the syntheses of a range of interesting polyalkyl-substituted benzenes.