5816-99-9

Upstream product

• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 90922-59-1 N-(4-methoxy-phenyl)-3-thio-malonamic acid 
• 5310-18-9 N-(4-methoxyphenyl)thioacetamide 
• 1593593-84-0 C₁₆H₁₄N₄O₄ 
• 1593593-81-7 1-(2-(4-methoxyphenylamino)-6-nitroimidazo[1,2-a]pyridine-3-yl)ethanone 
• 1593593-89-5 4-acetyl-3-(4-methoxyphenylamino)isoxazol-5(2H)-one 
• 1593593-79-3 4-acetyl-3-(4-methoxyphenylamino)-2-(5-nitropyridin-2-yl)isoxazol-5(2H)-one 

Relevant academic research and scientific papers

Net rearrangements of 4-acetyl-3-(4-substituted phenylamino)-2-(5- nitropyridin-2-yl)isoxazol-5(2H)-ones to imidazo [1,2-a]pyridines by Flash-Vacuum-Pyrolysis (F.V.P)

4-acetyl-3-(4-substituted phenylamino)-2-(5-nitropyridin-2-yl) isoxazol-5(2H)-ones, rearranged under Flash-Vacuum-Pyrolysis (F.V.P) conditions accompanied by elimination of carbon dioxide to give imidazo[1, 2-a]pyridines in high to excellent yields (90-95%).

A SYNTHETIC APPROACH TO 4-OXO AND 4-THIOXO AZETIDINONES FROM HETEROCUMULENES AND ESTER ENOLATES. A NOVEL SYNTHESIS OF 4-THIO-ACETOXY AZETIDIN-2-ONES.

The addition of the ester enolates (3) to the heterocumulenes (4), yields acyclic derivatives (5), which can be cyclized to the thio or to the oxo malonimides (1).A further elaboration of thiomalonimides (5a) and (5c) led to 4-thio-acetoxy azetidinones (1