58161-73-2Relevant articles and documents
In vitro anti-melanogenic effects of chimeric compounds, 2-(substituted benzylidene)-1,3-indanedione derivatives with a β-phenyl-α, β -unsaturated dicarbonyl scaffold
Ryu, Il Young,Choi, Inkyu,Jung, Hee Jin,Ullah, Sultan,Choi, Heejeong,Al-Amin, Md.,Chun, Pusoon,Moon, Hyung Ryong
, (2021/02/16)
Tyrosinase is considered a key contributor to melanogenesis, and safe, potent tyrosinase inhibitors are needed for medical and cosmetic purposes to treat skin hyperpigmentation and prevent fruit and vegetable browning. According to our accumulated SAR dat
Leishmanicidal and cytotoxic activities and 4D-QSAR of 2-arylidene indan-1,3-diones
de Souza, Ana P. M.,Costa, Maria C. A.,de Aguiar, Alex R.,Bressan, Gustavo C.,de Almeida Lima, Graziela D.,Lima, Wallace P.,Borsodi, Maria P. G.,Bergmann, Bartira R.,Ferreira, Márcia M. C.,Teixeira, Róbson R.
, (2021/08/03)
The indan-1,3-dione and its derivatives are important building blocks in organic synthesis and present important biological activities. Herein, the leishmanicidal and cytotoxicity evaluation of 16 2-arylidene indan-1,3-diones is described. The compounds w
Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease
Oliveira, Ana Flávia C. da S.,de Souza, Ana Paula M.,de Oliveira, André S.,da Silva, Milene L.,de Oliveira, Fabrício M.,Santos, Edjon G.,da Silva, ítalo Esposti P.,Ferreira, Rafaela S.,Villela, Filipe S.,Martins, Felipe T.,Leal, Daniel H.S.,Vaz, Boniek G.,Teixeira, Róbson R.,de Paula, Sergio O.
supporting information, p. 98 - 109 (2018/03/09)
A simple and efficient Knoevenagel procedure for the synthesis of 2-arylidene indan-1,3-diones is herein reported. These compounds were prepared via ZrOCl2·8H2O catalyzed reactions of indan-1,3-dione with several aromatic aldehydes and using water as the