58172-29-5Relevant academic research and scientific papers
Identification of Novel Macrocyclic Peptidase Substrates via On-Bead Enzymatic Cyclization
Hansen, Kristina K.,Hansen, Henrik C.,Clark, Ryan C.,Bartlett, Paul A.
, p. 8459 - 8464 (2007/10/03)
Peptidase-catalyzed formation of macrocyclic lactams on solid phase identifies ring systems that are favorably bound in the enzyme active site. We evaluated several cyclic peptide motifs linked by ester bonds between the P2 and P1′ or the P1 and P2′ side
Model Studies on Pepsin-Catalyzed Peptide Synthesis in a Biphasic Aqueous-Organic System
Kuhl, Peter,Wilsdorf, Andreas,Jakubke, Hans-Dieter
, p. 571 - 580 (2007/10/02)
The usefulness of biphasic aqueous-organic solvent systems for pepsin-catalyzed synthesis of model peptides Z-X-Phe-OMe (X = Ala, Gln, Leu) has been demonstrated by coupling the corresponding Z-X-Phe-OH with H-Phe-OMe.The influence of various organic solv
