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4-(4-Methoxy-phenoxy)-benzoic acid hydrazide is a chemical compound with the molecular formula C14H14N2O3. It is a derivative of benzoic acid, featuring a hydrazide group attached to the 4-position of the benzene ring, and a 4-methoxy-phenoxy group attached to the same position. 4-(4-methoxy-phenoxy)-benzoic acid hydrazide is known for its potential applications in pharmaceuticals and as a chemical intermediate. It is characterized by its ability to form various derivatives due to the presence of the hydrazide group, which can participate in condensation reactions to form hydrazones and other complex molecules. The compound's structure allows for a range of chemical modifications, making it a versatile building block in organic synthesis and drug development.

5818-08-6

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5818-08-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5818-08-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,1 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5818-08:
(6*5)+(5*8)+(4*1)+(3*8)+(2*0)+(1*8)=106
106 % 10 = 6
So 5818-08-6 is a valid CAS Registry Number.

5818-08-6Relevant academic research and scientific papers

Potent, selective pyrimidinetrione-based inhibitors of MMP-13

Reiter, Lawrence A.,Freeman-Cook, Kevin D.,Jones, Christopher S.,Martinelli, Gary J.,Antipas, Amy S.,Berliner, Martin A.,Datta, Kaushik,Downs, James T.,Eskra, James D.,Forman, Michael D.,Greer, Elaine M.,Guzman, Roberto,Hardink, Joel R.,Janat, Fouad,Keene, Nandell F.,Laird, Ellen R.,Liras, Jennifer L.,Lopresti-Morrow, Lori L.,Mitchell, Peter G.,Pandit, Jayvardhan,Robertson, Donald,Sperger, Diana,Vaughn-Bowser, Marcie L.,Waller, Darra M.,Yocum, Sue A.

, p. 5822 - 5826 (2007/10/03)

Using SAR from two related series of pyrimidinetrione-based inhibitors, compounds with potent MMP-13 inhibition and >100-fold selectivity against other MMPs have been identified. Despite high molecular weights, c log Ps, and polar surface areas, the compo

Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione metalloproteinase inhibitors

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Page/Page column 37, (2010/02/05)

The present invention relates to triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione; metalloproteinase inhibitors of the formula wherein X, A, Y, B, G, W, and R1 are as defined in the specification, and to pharmaceutical compositions and methods of treating inflammation, cancer and other disorders.

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