581813-08-3

Basic information

• Product Name: 5-Isoquinolinamine,1,3-dimethyl-(9CI)
• Synonyms: 5-Isoquinolinamine,1,3-dimethyl-(9CI)
• CAS NO: 581813-08-3
• Molecular Formula: C₁₁H₁₂N₂
• Molecular Weight: 172.22638
• Product Categories: ISOQUINOLINE
• Mol File: 581813-08-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Isoquinolinamine,1,3-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoquinolinamine,1,3-dimethyl-(9CI)(581813-08-3)
• EPA Substance Registry System: 5-Isoquinolinamine,1,3-dimethyl-(9CI)(581813-08-3)

Safety Data

• Hazardous Substances Data: 581813-08-3(Hazardous Substances Data)

Upstream product

• 1721-94-4 1,3-dimethylisoquinoline 
• 121221-13-4 1,3-dimethyl-5-nitroisoquinoline 

Downstream Products

• 581811-41-8 N-(4-tert-butylbenzyl)-N'-(1,3-dimethyl-5-isoquinolinyl)urea 
• 581811-65-6 N-(1,3-dimethyl-5-isoquinolinyl)-N'-[3-fluoro-4-(trifluoromethyl)benzyl]urea 
• 852241-30-6 N-(1,3-dimethyl-5-isoquinolinyl)-N'-[3-fluoro-4-(trifluoromethyl)benzyl]urea hydrochloride 
• 852241-25-9 N-(4-tert-butylbenzyl)-N'-(1,3-dimethyl-5-isoquinolinyl)urea hydrochloride 
• 1032117-95-5 C₂₀H₁₈F₃N₃O*ClH 
• 852241-20-4 N-(4-bromobenzyl)-N'-(1,3-dimethyl-5-isoquinolinyl)urea hydrochloride 

Relevant articles and documents

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).

Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor

Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.

UREA COMPOUNDS ACTIVE AS VANILLOID RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN

Certain compounds of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P', n, p, q, r and s are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds in medicine.